LUPON SCHOOL OF FISHERIES started as Lupon Community High School in 1969. Two years later, it became a Municipal High School. In 1982, the Sangguniang Bayan of Lupon passed a resolution recommending the conversion of the school into a School of Fisheries considering among others the need for such a school in the province being located along Davao Gulf and having vast area of brackish water fishpond in the area. The late Assemblyman Teodoro Palma Gil filed Parliamentary Bill No. 1642 and on November 15,1982 Batas Pambansa Bilang 298 was signed by then Pres. Ferdinand E. Marcos converting Lupon Municipal High School to Lupon School of Fisheries.

In 1991, the school acquired a 4.5 hectares fishpond area given by the Dacudao family through a Deed of Transfer of Rights without any single centavo paid by the government. In 1992, then Congressman Thelma Z. Almario gave P500,000 pesos from her Countryside Development Fund. Such fund was utilized in the purchase of 5.1 hectares land adjacent to the fishpond area. In 1992 the school started offering Two Year Diploma in Fishery Technology major in Aquaculture and Fish Processing.

With the passage of RA 7796 otherwise known as TESDA Law in 1994 the school was officially transferred to TESDA in March 1998.